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1

Divergence and complexities in DAG signaling: looking beyond PKC

ChengFeng Yang, Marcelo G Kazanietz

Journal:

Trends in Pharmacological Sciences

Year:

2003

Language:

english

File:

PDF, 404 KB

english, 2003

2

Transcriptional Regulation of Oncogenic Protein Kinase Cϵ (PKCϵ) by STAT1 and Sp1 Proteins

Wang, HongBin, Gutierrez-Uzquiza, Alvaro, Garg, Rachana, Barrio-Real, Laura, Abera, Mahlet B., Lopez-Haber, Cynthia, Rosemblit, Cinthia, Lu, Huaisheng, Abba, Martin, Kazanietz, Marcelo G.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 2.25 MB

english, 2014

3

Cucurbitacin I Inhibits Rac1 Activation in Breast Cancer Cells by a Reactive Oxygen Species-Mediated Mechanism and Independently of Janus Tyrosine Kinase 2 and P-Rex1

Lopez-Haber, C., Kazanietz, M. G.

Journal:

Molecular Pharmacology

Year:

2013

Language:

english

File:

PDF, 3.33 MB

english, 2013

4

P-REX1-Independent, Calcium-Dependent RAC1 Hyperactivation in Prostate Cancer

Baker, Martin J., Abba, MartÃn C., Garcia-Mata, Rafael, Kazanietz, Marcelo G.

Journal:

Year:

2020

Language:

english

File:

PDF, 2.05 MB

english, 2020

5

Rac-GEF/Rac Signaling and Metastatic Dissemination in Lung Cancer

Cooke, Mariana, Baker, Martin J., Kazanietz, Marcelo G.

Journal:

Frontiers in Cell and Developmental Biology

Year:

2020

Language:

english

File:

PDF, 1011 KB

english, 2020

6

Eyes wide shut: Protein kinase C isozymes are not the only receptors for the phorbol ester tumor promoters

Marcelo G. Kazanietz

Journal:

Molecular Carcinogenesis

Year:

2000

Language:

english

File:

PDF, 103 KB

english, 2000

7

Contribution of individual PKC isoforms to breast cancer progression

Alejandro J. Urtreger, Marcelo G. Kazanietz, Elisa D. Bal de Kier Joffé

Journal:

Year:

2012

Language:

english

File:

PDF, 610 KB

english, 2012

8

Cell growth inhibition by all-trans retinoic acid in SKBR-3 breast cancer cells: Involvement of protein kinase Cα and extracellular signal-regulated kinase mitogen-activated protein kinase

Shino Nakagawa, Teruhiko Fujii, Goro Yokoyama, Marcelo G. Kazanietz, Hideaki Yamana, Kazuo Shirouzu

Journal:

Molecular Carcinogenesis

Year:

2003

Language:

english

File:

PDF, 359 KB

english, 2003

9

Atypical protein kinase C-ζ modulates clonogenicity, motility, and secretion of proteolytic enzymes in murine mammary cells

Alejandro J. Urtreger, Valeria C. Grossoni, Karina B. Falbo, Marcelo G. Kazanietz, Elisa D. Bal de Kier Joffé

Journal:

Molecular Carcinogenesis

Year:

2005

Language:

english

File:

PDF, 250 KB

english, 2005

10

Protein kinase C δ enhances proliferation and survival of murine mammary cells

Valeria C. Grossoni, Karina B. Falbo, Marcelo G. Kazanietz, Elisa D. Bal de Kier Joffé, Alejandro J. Urtreger

Journal:

Molecular Carcinogenesis

Year:

2007

Language:

english

File:

PDF, 307 KB

english, 2007

11

PKC-mediated secretion of death factors in LNCaP prostate cancer cells is regulated by androgens

Liqing Xiao, Anatilde Gonzalez-Guerrico, Marcelo G. Kazanietz

Journal:

Molecular Carcinogenesis

Year:

2009

Language:

english

File:

PDF, 243 KB

english, 2009

12

Targeting protein kinase C and “non-kinase” phorbol ester receptors: Emerging concepts and therapeutic implications

Marcelo G. Kazanietz

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2005

Language:

english

File:

PDF, 301 KB

english, 2005

13

Conformationally constrained analogues of diacylglycerol (DAG). 3. Interaction of α-alkyl-γ-lactones with protein kinase C (PK-C)

Jeewoo Lee, Victor E. Marquez, Nancy E. Lewin, Marcelo G. Kazanietz, Afshin Bahador, Peter M. Blumberg

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 367 KB

english, 1993

14

Conformationally constrained analogues of diacylglycerol (DAG). 4. Interaction of α-alkylidene-γ-lactones with protein kinase C (PK-C)

Jeewoo Lee, Victor E. Marquez, Nancy E. Lewin, Afshin Bahador, Marcelo G. Kazanietz, Peter M. Blumberg

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 252 KB

english, 1993

15

Rational design, synthesis, and biological evaluation of rigid pyrrolidone analogues as potential inhibitors of prostate cancer cell growth

Lixin Qiao, Lian-Yun Zhao, Suo-Bao Rong, Xiong-Wu Wu, Shaomeng Wang, Teruhiko Fujii, Marcelo G Kazanietz, Laura Rauser, Jason Savage, Bryan L Roth, Judith Flippen-Anderson, Alan P Kozikowski

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 537 KB

english, 2001

16

Conformationally constrained analogues of diacylglycerol. 6. Changes in PK-C binding affinity for 3-O-acyl-2-deoxy-L-ribonolactones bearing different acyl chains.

Victor E. Marquez, Jeewoo Lee, Rajiv Sharma, Kelly Teng, Shaomeng Wang, Nancy E. Lewin, Afshin Bahador, Marcelo G. Kazanietz, Peter M. Blumberg

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 393 KB

english, 1994

17

Synthesis of ingenol analogs wth affinity for protein kinase C

Jeffrey D. Winkler, Bor-Cherng Hong, Afshin Bahador, Marcelo G. Kazanietz, Peter M. Blumberg

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1993

Language:

english

File:

PDF, 298 KB

english, 1993

18

Conformationally constrained analogues of diacylglycerol (DAG)-II. Differential interaction of δ-lactones and γ-lactones with protein kinase C (PK-C)

Jeewoo Lee, Victor E. Marquez, Peter M. Blumberg, Kristopher W. Krausz, Marcelo G. Kazanietz

Journal:

Bioorganic & Medicinal Chemistry

Year:

1993

Language:

english

File:

PDF, 612 KB

english, 1993

19

Hallmarks for senescence in carcinogenesis: novel signaling players

M. Cecilia Caino, John Meshki, Marcelo G. Kazanietz

Journal:

Year:

2009

Language:

english

File:

PDF, 534 KB

english, 2009

20

Opposite effects of protein kinase C beta1 (PKCβ1) and PKCε in the metastatic potential of a breast cancer murine model

Valeria C. Grossoni, Laura B. Todaro, Marcelo G. Kazanietz, Elisa D. Bal de Kier Joffé, Alejandro J. Urtreger

Journal:

Breast Cancer Research and Treatment

Year:

2009

Language:

english

File:

PDF, 478 KB

english, 2009

21

Protein kinase C δ inhibits the production of proteolytic enzymes in murine mammary cells

Valeria C. Grossoni, Karina B. Falbo, Laura V. Mauro, Martín A. Krasnapolski, Marcelo G. Kazanietz, Elisa D. Bal De Kier Joffé, Alejandro J. Urtreger

Journal:

Clinical and Experimental Metastasis

Year:

2007

Language:

english

File:

PDF, 318 KB

english, 2007

22

Synthesis of two rigid diacylglycerol analogues having a perhydro furo[3,2-b]furan bis-γ-butyrolactone skeleton. 3.

Jeewoo Lee, Victor E. Marquez, Afshin Bahador, Marcelo G. Kazanietz, Peter M. Blumberg

Journal:

Tetrahedron Letters

Year:

1993

Language:

english

File:

PDF, 261 KB

english, 1993

23

Protein kinase C and other diacylglycerol effectors in cancer

Griner, Erin M., Kazanietz, Marcelo G.

Journal:

Nature Reviews Cancer

Year:

2007

Language:

english

File:

PDF, 802 KB

english, 2007

24

Phospholipase Cγ/diacylglycerol-dependent activation of β2-chimaerin restricts EGF-induced Rac signaling

Wang, HongBin, Yang, Chengfeng, Leskow, Federico Coluccio, Sun, Jing, Canagarajah, Bertram, Hurley, James H, Kazanietz, Marcelo G

Journal:

The EMBO Journal

Year:

2006

Language:

english

File:

PDF, 696 KB

english, 2006

25

Modulation of noradrenaline release by presynaptic alpha-2 and beta adrenoceptors in rat atria

Marcelo G. Kazanietz, María Amelia Enero

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1989

Language:

english

File:

PDF, 642 KB

english, 1989

26

Role of cyclic AMP in the release of noradrenaline from isolated rat atria

Marcelo G. Kazanietz, Maria Amelia Enero

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1992

Language:

english

File:

PDF, 439 KB

english, 1992

27

Cardiovascular effects of alpha-adrenergic drugs: Differences between clonidine and guanabenz

J. S. Gutkind, M. Kazanietz, M. A. Enero

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1986

Language:

english

File:

PDF, 622 KB

english, 1986

28

Beta-adrenoceptor desensitization by clenbuterol in rat uterus

Guillermo F. Bramuglia, Marcelo G. Kazanietz, Ernesto Pezman, María Amelia Enero

Journal:

General Pharmacology: The Vascular System

Year:

1993

Language:

english

File:

PDF, 430 KB

english, 1993

29

Cell cycle- and protein kinase C-specific effects of resiniferatoxin and resiniferonol 9,13,14-ortho-phenylacetate in intestinal epithelial cells

Mark R Frey, Jennifer A Clark, Nicholas W Bateman, Marcelo G Kazanietz, Adrian R Black, Jennifer D Black

Journal:

Biochemical Pharmacology

Year:

2004

Language:

english

File:

PDF, 633 KB

english, 2004

30

Rac signaling in breast cancer: A tale of GEFs and GAPs

Eva Wertheimer, Alvaro Gutierrez-Uzquiza, Cinthia Rosemblit, Cynthia Lopez-Haber, Maria Soledad Sosa, Marcelo G. Kazanietz

Journal:

Cellular Signalling

Year:

2012

Language:

english

File:

PDF, 840 KB

english, 2012

31

Protein Kinase C Regulation: C1 Meets C-tail

Marcelo G. Kazanietz, Mark A. Lemmon

Journal:

Year:

2011

Language:

english

File:

PDF, 242 KB

english, 2011

32

Histamine acting on H1 receptor promotes inhibition of proliferation via PLC, RAC, and JNK-dependent pathways

Cintia Notcovich, Federico Diez, Maria Rosario Tubio, Alberto Baldi, Marcelo G. Kazanietz, Carlos Davio, Carina Shayo

Journal:

Experimental Cell Research

Year:

2010

Language:

english

File:

PDF, 1.19 MB

english, 2010

33

Pharmacology of the receptors for the phorbol ester tumor promoters: Multiple receptors with different biochemical properties

Marcelo G Kazanietz, Marı́a J Caloca, Pilar Eroles, Teruhiko Fujii, Marı́a L Garcı́a-Bermejo, Muredach Reilly, HongBin Wang

Journal:

Biochemical Pharmacology

Year:

2000

Language:

english

File:

PDF, 575 KB

english, 2000

34

Biochemical and immunological studies of protein kinase C from Trypanosoma cruzi

Marı́a L. Gómez, Claudia M. Ochatt, Marcelo G. Kazanietz, Héctor N. Torres, M.Teresa Téllez-Iñón

Journal:

International Journal for Parasitology

Year:

1999

Language:

english

File:

PDF, 175 KB

english, 1999

35

Protein Kinase C in Cancer Signaling and Therapy Volume 7417 || Regulation and Function of Protein Kinase D Signaling

Kazanietz, Marcelo G.

Year:

2010

Language:

english

File:

PDF, 571 KB

english, 2010

36

Rho GEFs and Cancer: Linking Gene Expression and Metastatic Dissemination

Barrio-Real, L., Kazanietz, M. G.

Journal:

Science Signaling

Year:

2012

Language:

english

File:

PDF, 1018 KB

english, 2012

37

Phosphorylation of the Catalytic Subunit of Rat Renal Na+,K+-ATPase by Classical PKC Isoforms

Marcelo G. Kazanietz, Maria J. Caloca, Oleg Aizman, Susana Nowicki

Journal:

Archives of Biochemistry and Biophysics

Year:

2001

Language:

english

File:

PDF, 217 KB

english, 2001

38

Differential Activation of PKC Isozymes by 14-3-3 ζ Protein

P. Acs, Z. Szallasi, M.G. Kazanietz, P.M. Blumberg

Journal:

Biochemical and Biophysical Research Communications

Year:

1995

File:

PDF, 347 KB

1995

39

Interaction between β2- and α2-adrenoceptor responses in the vascular system: effect of clenbuterol

Marcelo G. Kazanietz, Jorge S. Gutkind, María Amelia Enero

Journal:

European Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 354 KB

english, 1986

40

Relaxant effect of benzodiazepines on uterine rings isolated from estrogen-treated rats

Marcelo G. Kazanietz, A.Belén Elgoyhen

Journal:

European Journal of Pharmacology

Year:

1990

Language:

english

File:

PDF, 299 KB

english, 1990

41

Decreased β-adrenoceptor-mediated vasodilation in aorta from aged rats: possible involvement of a stimulatory GTP-binding protean

Marcelo Gabriel Kazanietz, María Amelia Enero

Journal:

European Journal of Pharmacology

Year:

1991

Language:

english

File:

PDF, 441 KB

english, 1991

42

C1 domains exposed: From diacylglycerol binding to protein–protein interactions

Francheska Colón-González, Marcelo G. Kazanietz

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2006

Language:

english

File:

PDF, 437 KB

english, 2006

43

Structural Mechanism for Lipid Activation of the Rac-Specific GAP, β2-Chimaerin

Bertram Canagarajah, Federico Coluccio Leskow, Jonathan Yew Seng Ho, Harald Mischak, Layla F. Saidi, Marcelo G. Kazanietz, James H. Hurley

Journal:

Year:

2004

Language:

english

File:

PDF, 607 KB

english, 2004

44

The RacGAP β2-Chimaerin Selectively Mediates Axonal Pruning in the Hippocampus

Martin M. Riccomagno, Andrés Hurtado, HongBin Wang, Joshua G.J. Macopson, Erin M. Griner, Andrea Betz, Nils Brose, Marcelo G. Kazanietz, Alex L. Kolodkin

Journal:

Year:

2012

Language:

english

File:

PDF, 3.15 MB

english, 2012

45

Recombinant C1b domain of PKCδ triggers meiotic maturation upon microinjection in Xenopus laevis oocytes

Pilar Aroca, Eugenio Santos, Marcelo G Kazanietz

Journal:

Year:

2000

Language:

english

File:

PDF, 121 KB

english, 2000

46

PKC isozymes and diacylglycerol-regulated proteins as effectors of growth factor receptors

Oliva, José Luis, Oliva, José Luis, Griner, Erin M., Oliva, José Luis, Griner, Erin M., Kazanietz, Marcelo G.

Journal:

Year:

2005

Language:

english

File:

PDF, 385 KB

english, 2005

47

A Host GPCR Signaling Network Required for the Cytolysis of Infected Cells Facilitates Release of Apicomplexan Parasites

Millholland, Melanie G., Mishra, Satish, Dupont, Christopher D., Love, Melissa S., Patel, Bhumit, Shilling, Dustin, Kazanietz, Marcelo G., Foskett, J. Kevin, Hunter, Christopher A., Sinnis, Photini, G

Journal:

Cell Host & Microbe

Year:

2013

Language:

english

File:

PDF, 2.50 MB

english, 2013

48

Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol

Gutierrez-Uzquiza, Alvaro, Colon-Gonzalez, Francheska, Leonard, Thomas A., Canagarajah, Bertram J., Wang, HongBin, Mayer, Bruce J., Hurley, James H., Kazanietz, Marcelo G.

Journal:

Nature Communications

Year:

2013

Language:

english

File:

PDF, 1.95 MB

english, 2013

49

Protein Kinase C in Cancer Signaling and Therapy || PKCs as Mediators of the Hedgehog and Wnt Signaling Pathways

Kazanietz, Marcelo G.

Year:

2010

Language:

english

File:

PDF, 691 KB

english, 2010

50

Protein Kinase C in Cancer Signaling and Therapy ||

Kazanietz, Marcelo G.

Year:

2010

Language:

english

File:

PDF, 6.51 MB

english, 2010

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